Roger and Kesner (2003)

Uses: Animal study / neurotransmission

Aim: Investigate the role of acetylcholine in the formation of spatial memory.

Method: Experiment

PROCEDURE:

  1. get the mice used to the maze.

  2. Mice were randomly allocated to one or two conditions, the rats were either injected with scopolamine or with the saline solutions 10 minutes before running the maze.

  3. Encoding was measured by the difference in average mistakes made on the start of day 1 and end of day 1.

  4. Then end of day 2 is compared to the end of day 1.

RESULTS:

Mice injected with scopolamine were slower than the other group in encoding but their retrieval speed are similar.

 

CONCLUSIONS:

Scopolamine decreases the speed which the mice found the route which means acetylcholine does play a role within the formation of new spatial information.

Evaluation:

  • refer to animal studies